Extinguishing the Burnout Epidemic: 4 Ingredients for Stress, Sleep and Mood Formulations
77% of consumers report suffering from work-related stress and the World Health Organization now recognizes “Burnout” as a chronic condition. The effects of stress can be felt in a myriad of ways, sleep being the most prominent with 48% of people in the U.S. report having sleep issues caused by stress. Elevated stress levels have been shown to influence the structural organization of sleep, including the duration of each sleep stage. This lack of quality sleep can further perpetuate the stress response creating a destructive cycle.
While the natural products industry cannot resolve the cultural norms that have brought about the Burnout epidemic, manufacturers can provide natural support to the significant number of consumers navigating both acute and chronic levels of stress, anxiety and fatigue. Maypro offers several powerful, science-backed ingredients that support these health areas.
Award-Winning Cognitive Support for Stress, Sleep and Focus
We know that chronic and acute stress negatively impacts not only sleep, but cognition—including memory and reasoning.*
Award-winning ETAS® can support healthy stress relief, sleep, and brain function.*
ETAS® is derived from the tough lower portion of asparagus stalks that would otherwise go to waste, making the ingredient both upcycled and sustainable. The extraction process used to create ETAS® asparagus extract powder results in unique hydroxymethyl furfural derivatives — particularly asfural — that are not contained in raw asparagus extract.
ETAS® asparagus extract powder works by increasing the production of Heat Shock Protein 70 (HSP70) — an intracellular protein produced naturally by the body when it encounters a stressor, such as extreme heat.*
HSP70 has many beneficial functions. HSP helps proteins to ensure correct folding and it repairs damaged cells, tipping the balance from excitatory cytokines to inhibitory ones and serves as an antioxidant.* Unfortunately, the heat shock response to stressors of all kinds decreases with age.
Double-blind, placebo-controlled research has shown a 300 mg dose of ETAS® effectively:
- Increases quality of sleep*
- Alleviates occasional stress by improving heart rate variability*
- Suppresses cortisol level increase*
- Raises cognitive performance, reduces fatigue and improves the stress response*
A Melatonin-Alternative with Clinical Research
Derived from a patented, purified, powdered extract of Apocynum venetum, Venetron® is a melatonin-alternative with great potential to improve mood and sleep.
Venetron is a stress-combating, mood-supporting and sleep-enhancing ingredient that doesn’t impact the CYP3A pathway. Effective at just 50mg per day, Venetron works by:
- Reducing the secretion of stress marker chromogranin A
- Promoting serotonin levels
- Supporting the natural production of melatonin
- Working in synergy with GABA
Venetron has been shown in several placebo-controlled human clinical trials to:
- Support a positive outlook*
- Alleviate occasional stress*
- Improve sleep quality*
More clinical studies are due to be published this year. To stay up to date on the latest Venetron research, click here to request a copy.
Support Anxiety Relief with Complete Spectrum CBDA
Cannabidiolic acid (CBDA) is the main phytocannabinoid in fiber and seed-oil hemp (Cannabis sativa L.) plants, but, according to researchers, its potential health-related capabilities were overshadowed for years by a greater scientific interest in its derivative, cannabidiol (CBD).
In addition, the production of CBDA is very difficult and most extraction methods, for example those which use CO2, cannot keep CBDA from decarboxylating into CBD.
Using a patented extraction method, the natural complete spectrum CBDA content of Cannabid-ALL™ is maintained from plant to extract, preserving more of hemp’s natural and beneficial health properties.
Cannabid-ALL features the highest amount of CBDA available, less than 0.3% THC, plus hemp flower constituents including polyphenols and chlorophyll. This makes Cannabid-ALL a full-spectrum extract that features:
- Better absorbability
- Most complete and advanced form of CBD
- Free-flowing powder mixes easily with other powder ingredients
- Enhanced effects against stress and anxiety*
- Supports the accurate targeting of joint issues—CBDA is a selective inhibitor of the inflammatory enzyme, COX-2*
Manufactured in a Current Good Manufacturing Practice (cGMP) facility certified by UL Solutions, each batch of Cannabid-ALL is independent-laboratory tested to confirm:
- Highest content of CBDA available and naturally occurring compounds—cannabinoids, sesquiterpenes, triterpines, flavonoids, chlorophyll
- Less than 0.3% THC
- Undetectable heavy metals, pesticides, mycotoxins and microorganisms
Boost Serotonin with 5-HTP
With an increased consumer focus on the effects of mood and stress on mental well-being, 5-HTP is an ingredient that should be at the top of formulators minds.
5-HTP is a chemical byproduct of the protein building block L-tryptophan. 5-HTP works in the brain and central nervous system by increasing the production of the chemical serotonin. Serotonin can affect sleep, appetite, temperature, sexual behavior, and pain sensation.
Since 5-HTP increases serotonin levels, it is used for conditions in which serotonin is believed to play an important role.* Talk to your Maypro representative today about including 5-HTP in your supplement formula.
