Published: October 22, 2026

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In a Supplier Insights Q&A with Nutraceuticals World, Maypro’s Lauren Clardy explains how ETAS® approaches stress and sleep through cellular resilience.

Clardy describes heat shock proteins as molecular chaperones that help cells protect and repair proteins under stress, noting that HSP70 and the body’s heat shock response tend to weaken with age.

Unlike melatonin, ETAS® does not act on the sleep-wake hormone. The asparagus stem extract contains compounds called asparaprolines that are linked to HSP70 induction, which may help the body adapt to everyday stress and balance stress with recovery.

She also unpacks the “Hot Spring in a Capsule” description, comparing the ingredient’s HSP70 activity to the heat exposure people have long sought in thermal baths.

ETAS® is upcycled from the lower part of the asparagus stalk and has been studied in six human clinical trials covering stress response, autonomic function, sleep and fatigue.


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