L-92®

Lactic acid bacteria are a well-studied group of beneficial bacteria with multiple documented health benefits. Lactobacillus acidophilus is the most well-known species of lactic acid bacteria, as it occurs in yogurt and many other foods.  

Produced from sterilized cells of a proprietary strain of Lactobacillus acidophilus, L-92 is a patented, powdered food ingredient that has been studied in both adults and children.

 

Atopic Dermatitis  

L-92 primarily works to promote dermal health, by moisturizing the skin and promoting comfort.  

A double-blind placebo-controlled study showed oral administration of L-92, in conjunction with a topical steroid treatment, helped to improve symptoms of atopic dermatitis in children. Researchers concluded it does so by mediating changes in the Th1-Th2 cytokine balance that results in lower levels of allergen specific immunoglobulin E in the blood. 

Seasonal Allergy  

During allergy season, L-92 supplementation promotes relief of congestion and ocular symptoms common with seasonal illnesses. By balancing cytokines in the blood, L-92 has proven to be one of the most effective tools when combatting seasonal allergens.


Winner of the NutrAward for Best Functional Ingredient in 2016, the GRAS ingredient L-92 has been shown in placebo-controlled human clinical research to: 

  • Demonstrate improvement in immune parameters and immune expression(1) 
  • Show potential to modulate the gut microbiome(1) 
  • Promote dermal health, moisture, and comfort*(2) 
  • Provide seasonal support for the health of the nasal mucosa*[3] 
  • Provide seasonal support for ocular comfort*[4]
  • L-92 has been studied in and is safe for Adults, Children and Dogs 

Immune Health 

A randomized, double-blind placebo-controlled study demonstrated L-92's expanded efficacy in supporting immune health (1). 

During an 8-week period, 180 healthy adults received either L-92 or a placebo tablet. The results showed the supplemented participants underwent improvements in local symptoms, such as cough, sore throat, fatigue and chills. 

The supplemented participants experienced activation of plasmacytoid dendritic cells (pDCs), which, in addition to their innate protective function, are key players in shaping our body's adaptive response to viruses. 
 
L-92 was even shown to aid the health of the all-important microbiome. 

Please click here to view a video that demonstrates how lactic acid bacteria is transported to cells in the immune system. 

 

STATUS

FUNCTIONS

DELIVERY FORMATS

CapsulesTabletsGummies

DOSAGE

21mg daily

    MECHANISM OF ACTION

    Lactobacillus acidophilus is believed to help balance cytokine levels.* Specifically, it may help tip the balance from excitatory to inhibitory cytokines by lowering levels of immunoglobin E in the blood, thus modulating the ratio between T-helper type 1 cells and T-helper type 2 cells.*[5],[6]

    SAFETY

    Lactic acid bacteria occur naturally in the human gut. They are used as starters for fermented dairy and non-dairy foods such as yogurt, butter, cheese, kefir, wine, and sauerkraut, and so are widely consumed. In addition, they have been extensively tested for safety and efficacy in human subjects.

    REFERENCES

    1.Sasai M, et al. Jpn Pharmacol Ther. 2022;50(9):1699–1707. 

    2.Torli S, et al. International Archives of Allergy and Immunology. 2011;154(3):236-245. 

    3.Ishida Y et al. Journal of Dairy Science. 2005 Feb;88(2):527-533. 

    4. Ishida Y, et al. Bioscience, Biotechnology, Biochemistry. 2005 Sep;69(9):1652-1660. 

    5. Torli S, et al, 2011. 

    6. Ishida Y, et al, 2005 Sep.