Clonapure®

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CREATINE THAT GOES TO WORK FASTER

Creatine is the most widely researched sports nutrition supplement available. It’s been clinically shown to improve athletic performance and increase lean muscle mass, all while boasting an excellent safety profile.* Research suggests this energy-generating molecule also has cognitive benefits such as supporting memory, attention time, and information processing speed.*1

The problem? Standard creatine monohydrate takes 3-4 weeks to take full effect, unless a large loading dose is taken (typically 20 g/day for 5-7 days).

Clonapure® is a faster creatine. A perfectly balanced blend of creatine monohydrate, phosphocreatine, and phosphate, Clonapure® requires no loading and is immediately available to muscle cells. This translates to:

  • More energy*
  • Shorter recovery*
  • Better performance*
  • Increased endurance*

Faster acting

Clonapure® contains phosphocreatine, the body’s preferred form of creatine for both immediate use and long-term storage. Unlike creatine monohydrate, which needs to be converted before it can be utilized, phosphocreatine is already in the body-ready, active form. As a result, Clonapure® goes to work on day one to quickly regenerate ATP—the primary energy source for muscle contractions, nerve impulses, and the synthesis of new molecules.*

More stable

Clonapure® is 25% more stable than creatine monohydrate, thanks to its patented composition of creatine monohydrate, phosphocreatine, and phosphate. This makes it easy to formulate into a variety of formats.

Faster Absorption

Human absorption data shows Clonapure® leads to a faster rate to reach sustained plasma creatine than creatine monohydrate.

Researched benefits

  • Preclinical research suggests Clonapure® enhances ATP synthesis within muscle cells more effectively than creatine monohydrate—a key factor in cellular energy production.*2
  • A four-week randomized, double-blind, placebo-controlled study of elite female volleyball players found Clonapure® improved players’ peak and mean power, reduced fatigue, and improved endurance.*1

STATUS

Dairy FreeGluten FreeVeganHalalKosher

FUNCTIONS

Sports NutritionHealthy AgingBone and JointCognitive HealthWomen's HealthMen's Health

MECHANISM OF ACTION

Creatine supports the production of ATP, the body’s primary energy molecule. Within muscle cells, creatine monohydrate is converted into phosphocreatine through the addition of a phosphategroup from ATP, forming ADP. When energy demand is high, phosphocreatine donates its phosphate back to ADP, rapidly regenerating ATP.   

Clonapure® enhances this natural energy cycle by delivering phosphocreatine directly for immediate ATP regeneration, while also supplying creatine monohydrate and phosphate to sustain ATP production over time.* 

Pre-clinical research suggests Clonapure® helps muscle cells synthesize ATP more effectively than creatine monohydrate alone.*  

SAFETY

In 2017, the International Society of Sports Nutritionreviewed the literature on creatine andconcludedthat“short and long-term supplementation (up to 30 g/day for 5 years) is safe and well-tolerated in healthy individuals and in a number of patient populations ranging from infants to the elderly.”3

References 

  1. Colletti A, Pellizzato M, Hernández-Bueno A, et al. Effects of Clonapure® Supplementation on Intermittent Aerobic Capacity and Explosive Power in Elite Female Volleyball Players. Int J Sports Sci Phys Educ. 2025;10(3):115-123. doi:10.11648/j.ijsspe.20251003.15 
  2. Lapena-Luzon T, Hernadez-Bueno A, et al. Evaluation of the Effect of Clonapure® Versus Creatine Monohydrate o ATP Levels in a C2C12 Muscle Cell Line. American Journal of Sports Science 2025;13:2: 50-56. doi.org/10.11648/j.ajss.20251302.14  
  3. Kreider RB, Kalman DS, Antonio J, et al. International Society of Sports Nutrition position stand: safety and efficacy of creatine supplementation in exercise, sport, and medicine. J Int Soc Sports Nutr. 2017;14:18. doi:10.1186/s12970-017-0173-z