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Sirtmax®

Increasingly, scientists who study aging have focused their attention on a group of protective genes called sirtuins, especially SIRT1 (known as “the longevity gene”). SIRT1 “recharges” mitochondria — the “power plants” of the cells — which tend to wind down with age. Therefore, any substance that can enhance the SIRT1 gene pathway is of great interest to anti-aging researchers.

Resveratrol is well-known for this effect. Now, there’s another natural ingredient that works in the same way, but is five times more potent (See graph below): Sirtmax®. Derived from the rhizome of black turmeric (Kaempferia parviflora) and rich in polymethoxyflavonoids, patented ingredient Sirtmax® could be the anti-aging ingredient you’re looking for.

A double-blind, placebo-controlled human study with 27 subjects found that taking 100 mg of Sirtmax® daily for seven weeks[1]:

  • Caused a reduction in body weight*
  • Helped maintain blood sugar levels already within a normal range*
  • Decreased the production of advanced glycation end products (AGES)
  • Showed a trend toward improvement in arterial flexibility*

 

Our journey begins in Thailand, one of the world’s leading producers of quality Kaempferia parviflora, commonly known as black turmetic.. Did you know that black turmeric upregulates a group of protective genes?. One of these genes, SIRT1, which is also known as the longevity gene, helps protect the mitochondria from decay and influences numerous genes that relate to aging effects.

 

Sirtmax has been developed to target precisely this gene.. It's made from the rhizome of black turmeric, which has been proven in in vitro studies to inhibit pancreatic lipase and glycation, a reaction that often causes oxidative damage to the system. Sirtmax works to prevent these breakdowns, and to protect the longevity of cells.

The effects of the SIRT1 gene may sound similar to that of those found inResveratrol., which has been a favourite  for anti-aging researchers. However, Sirtmax is proven to be 5 times more potent than Resveratrol, making it the perfect partner for low-dose mechanisms. (Andrew, can you clarify what the 5 times is referring to? 5 times in terms of what? I recommend being more specific).

Sirtmax was found to help significantly improve metabolic and cardiovascular health. In a double-blind placebo human clinical trial, Sirtmax was found to successfully cause a reduction in bodyweight, help maintain blood sugar levels within a normal level, decrease production of advanced glycation end products, and showed improvement in arterial flexibility.

Protect yourself by protecting your cells, with the power of Sirtmax!

STATUS

FUNCTIONS

    Origin: Thailand

    Derived from the plant Kaempferia parviflora , native to Thailand

    MECHANISM OF ACTION

    Animal and in vitro research has shown that black turmeric inhibits pancreatic lipase (a fat-digesting enzyme) and glycation, a reaction that can cause oxidative damage.[2],[3] In addition, it has a favorable impact on adipogenesis (fat cell differentiation) and the secretion of adiponectin, which regulates glucose levels.[4]

    SAFETY

    Black turmeric is related to both turmeric and ginger. One of the most popular herbal medicines in Thailand and Laos, it has been safely consumed as a revitalizing drink for years. A double-blind, placebo-controlled human study on Sirtmax® found no adverse effects.

    [1] Shimada N, et al. The safety and efficacy of Kamepferia parviflora extract (SIRTMAX®) on healthy volunteers. 2012. Unpublished paper.

    [2]Shimada T, et al. Preventive effect of Kaempferia parviflora ethyl acetate extract and its major components polymethoxyflavonoid on metabolic diseases. Fitoterepia. 2011;82:1272-78

    [3] Nakata A, et al. Potent SIRT1 enzyme-stimulating and anti-glycation activities of polymethoxyflavonoids from Kaempferia parviflora. Natural Products Communications. 2014;9(9):1291-4.

    [4] Horikawa T, et al. Polymethoxyflavonoids from Kaempferia parviflora induce adipogenesis on 3T3-L1 preadipocytes by regulating transcription factors at an early stage of differentiation. Biol Pharm Bull. 2012;35(5):686-92.

    Contact us today for purchasing information and SAMPLES so you can start formulating with our ingredients.

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