Biotics Partner

The demand for biotics continues to grow as consumers seek support for gut health, immune resilience, digestive regularity, and targeted wellness. Maypro offers a comprehensive portfolio spanning prebiotics, probiotics, and postbiotics to meet today’s evolving health needs.

According to the International Probiotics Association, the global market for probiotic supplements reached $9.4 billion in 2023, with a CAGR of 7.5% predicted through 2027. Meanwhile, the prebiotics market is estimated to grow at a CAGR of 14.9% through 2030, Grand View Research data shows.

From prebiotics to probiotics and postbiotics, Maypro offers a curated selection of proven ingredients, many of which can be synergistically combined to create next-generation synbiotics.

Maypro Prebiotics

Prebiotics feed and nourish gut bacteria to help them flourish. Primarily, prebiotics are plant fibers, and there is a wide range suitable for product development.

Prebiotics are non-digestible plant fibers that selectively stimulate the growth and activity of beneficial gut bacteria, contributing to a balanced and healthy microbiome. By serving as a food source for specific bacterial populations, prebiotics help promote gut health, support immune function, and enhance overall well-being.

Maypro’s unique prebiotics have additional, naturally occurring benefits.

AppleActiv® DAPP: Prebiotic Support from Apple Peel

AppleActiv Lady

AppleActiv® DAPP (Dried Apple Peel Powder) is a rich source of soluble fiber, notably pectin, along with an array of polyphenols and phytonutrients. The pectin and other complex carbohydrates in apple peel serve as fermentable substrates for beneficial gut bacteria. Research indicates that these fibers promote the growth of butyrate-producing bacteria, such as Faecalibacterium prausnitzii and Roseburia species, which are key contributors to gut health. The production of short-chain fatty acids (SCFAs), particularly butyrate, plays a critical role in maintaining intestinal barrier function, modulating inflammation, and supporting overall digestive and metabolic health. By favorably shifting the composition of the gut microbiota, AppleActiv® DAPP offers a natural and effective prebiotic solution for targeted gut health support.

Champex®

Champex

Champex®: The versatile functional mushroom, champignon (Agaricus bisporus), is a well-studied prebiotic shown to elevate production of Prevotella, a beneficial bacteria genus in the gut. Research finds that champignon acts as a prebiotic that enhances carbohydrate metabolism and increased butyrate production, resulting in improved intestinal epithelial barrier protection. https://pmc.ncbi.nlm.nih.gov/articles/PMC6266512/

Champex is also distinguished by its clinically shown ability to detoxify and reduce endogenously produced odors through methanethiol and allythiol reactions and reducing quantities of putrefactive bacteria.

EubioQuercetin™

Champex

EubioQuercetin™: This winner of the 2024 Natural Choice Best Botanical Ingredient Award is an antioxidant and prebiotic rolled into one. EubioQuercetin™, a 100% natural quercetin with rutinose derived from the Japanese pagoda tree (Sophora japonica), is a natural high-absorption alternative to enzymatically treated quercetin. It is unique from other quercetin sources as it is 6,500 times more water-soluble and has an ORAC score 1,300 times greater; plus it is shown effective at a low daily dose of 125 mg. Rutinose is a non-digestible disaccharide and acts as a prebiotic. A 2024 study indicated that EubioQuercetin™ increases beneficial bacteria in the colon where they help produce short-chain fatty acids that support metabolic, cardiovascular, gut, and immune health, as well as the oxidative stress response.


Maypro Probiotics

Research into probiotic strains shows precise actions and health benefits, allowing for more targeted product development. Human residential bacteria (HRB), which naturally reside in the human microbiome, appear to induce more significant benefits than non-HRB. Maypro’s specialized HRB probiotics are useful for a host of products.

Morinaga B-3™: Support Healthy Weight—Naturally

Morinaga B-3

Bifidobacterium breve is a species of HRB that reside in the intestines of human newborns, and the strain Morinaga B-3™ is clinically demonstrated to promote healthy metabolism and weight management. A 12-week study showed reduction of body fat and weight loss compared to baseline and placebo. A newer 12-week study confirmed these effects, showing significant body fat mass loss and reduction in body fat percentage. Both studies suggest that the strain is a perfect addition to GLP-1-support formulas.

Morinaga BB536™: Daily Defense for Gut and Immune Balance

Morinaga BB536

Supported by more than 250 studies, this HRB strain has a powerful foundation of clinical proof demonstrating its efficacy in promoting and improving digestive function and overall gut health. A more recent human RCT shows that after two weeks of BB536 supplementation, individuals with persistent constipation experienced increased bowel movement frequency.

Morinaga M-16V®: Clinically Trusted. Infant Safe

Morinaga M-16V

Morinaga M-16V®, a proprietary strain of Bifidobacterium breve, was awarded the 2019 NutraIngredients-Asia Award for Infant Nutrition. Clinically studied, M-16V® supports gut health by promoting beneficial bacterial colonization, strengthening intestinal barrier function, and modulating immune responses. Research also shows benefits for respiratory health by reducing inflammatory pathways, and for skin health through the gut-skin axis. Its strong clinical profile makes M-16V® a versatile probiotic for infant and family health formulations.

Morinaga M-63®: Gentle, Clinically Proven Probiotic for Infant and Gut Health

Morinaga M-63

M-63® is a well studied strain of Bifidobacterium longum subsp. longum, originally isolated from the healthy intestinal flora of infants known for its gut-colonizing ability, and gentle immunomodulatory effects. This strain is naturally suited for early-life microbiome support and safe for use in sensitive populations—including infants, toddlers, pregnant women, and older adults. M- 63® is a human-residential strain, freeze-dried, heat-tolerant, and stable in blends with a broad formulation pH range.

"A study suggested that M-63® may help restore microbiota balance between Bacteroides and Firmicutes, potentially supporting digestive health and a balanced gut-brain axis. As the incidence of IBS-related discomfort continues to rise, this HRB strain may be beneficial for promoting a healthy stress-response and gastrointestinal function."


Maypro Postbiotics

According to the International Scientific Association of Probiotics and Prebiotics (ISAPP), a postbiotic is defined as a “preparation of inanimate microorganisms and/or their components that confers a health benefit.” And because they are inanimate, postbiotics don’t raise concerns about shelf stability and viability. Postbiotics are increasingly being studied and have thus far been shown to influence inflammatory processes, immunomodulation and more. Maypro’s postbiotics are backed by human clinicals.

KT-11™: Immunobiotic Support for Allergies and Oral Health

KT-11

KT-11™ is a heat-sterilized strain of Lactobacillus crispatus, known for its immunomodulatory properties. By balancing Type 1 (Th1) and Type 2 (Th2) T-helper cells, KT-11™ helps reduce allergic responses. Additionally, a 4-week study demonstrated a statistically significant reduction in Porphyromonas gingivalis (P. gingivalis), a key pathogen in periodontal disease, compared to placebo. These benefits make KT-11™ an effective solution for supporting immune health and promoting oral hygiene.

L-92®: Probiotic Support for Skin and Respiratory Health

L-92

L-92® is a heat-killed Lactobacillus acidophilus strain shown to modulate immune responses by balancing Th1 and Th2 cytokines. This modulation supports immune tolerance and inflammation regulation.

In clinical studies, L-92® has demonstrated benefits for skin health, with a 24-week trial showing improvements in atopic dermatitis, including reduced scratching and better skin condition, linked to increased TGF-β and IL-12 levels. Additionally, it has shown effectiveness in alleviating allergic rhinitis symptoms, such as reduced nasal swelling and redness.

These findings highlight L-92®’s potential as a probiotic for skin and respiratory health through its immune-modulating properties.

LAC-Shield™ -Immune Support That Stands the Heat

Heat-Killed Lactobacillus paracasei

Lacshield

LAC-Shield™ is a heat-killed and highly stable strain of beneficial lactic acid bacteria with a clinically studied immuno-modulatory effect. A postbiotic that can complement prebiotics and probiotics in a wide variety of applications, Lac-Shield™ is part of the emerging postbiotic category—non-viable microbial cells that still confer health benefits. It delivers immune support without the need for refrigeration or survival through the gut.

Lac- Shield™ has been clinically studied to support immune function by enhancing production of IL-12 and promoting antigen-specific IgA production. Clinical studies suggest Lac-Shield® enhances mucosal immunity and supports protective antibody responses. Backed by published human clinical trials and pre-clinical research Lac- Shield™ has demonstrated benefits in elderly populations and healthy adults under immune stress (e.g., seasonal changes).

Lac-Shield® is versatile and helps brands deliver clinically backed immune support while retaining functional benefits across high-heat manufacturing processes and shelf-stable products.