Nutraceuticals World — Lactopeptides Supplement Supports Body Composition, Perceived Training Fatigue
Published: March 4, 2026
Lactopeptides Supplement Supports Body Composition, Perceived Training Fatigue
A clinical pilot study published in the Journal of Exercise and Nutrition found that daily supplementation with lactotripeptides (IPP and VPP), derived from casein, may support improvements in body composition and training performance. The 4-week study evaluated 34 healthy men aged 20–49 who maintained consistent training routines while receiving either 3.4 mg, 1.7 mg of lactotripeptides, or a placebo. Participants taking the 3.4 mg dose experienced notable improvements in muscle pump, thigh circumference, lean body mass, body weight, and BMI—indicators linked to hypertrophy and training adaptations. The treatment groups also reported reduced post-exercise fatigue and greater next-day motivation to train. No adverse events were observed, and blood and urine analyses indicated a strong safety profile. The findings suggest lactotripeptides may support exercise performance through improved blood flow and nitric-oxide–related mechanisms.
