Formulators developing products for beauty-from-within understand that collagen, while essential, isn’t sufficient on its own. For collagen to perform optimally, it must be supported by key co-factors—most notably, bioavailable silicium (Si), also known as silicon. Without silicium, collagen synthesis and stabilization are compromised, limiting the structural integrity that consumers seek from these supplements.
Silicium plays a critical role in the crosslinking and maturation of collagen fibers. It helps form the stable triple-helix structure that gives collagen its strength and function. Silicium enhances hydration and mechanical resilience throughout the connective tissue network and supports the structure and function of elastin, keratin, and proteoglycans—key components that influence the elasticity of skin and joints, as well as the strength of hair and nails. This broad connective tissue support makes silicium a powerful co-ingredient in formulations designed to improve skin firmness and enhance the resilience of hair and nails.
THE CHALLENGE WITH SILICIUM
Commercial-grade silicium, however, prevents challenges for formulators. Two of the most widely used forms of silicium in beauty-from-within dietary supplements are silica, also known as silicon dioxide (SiO2), and orthosilicic acid (OSA). While both serve as sources of silicium (elemental silicon), they present stability, solubility, and bioavailability issues.
Silicon Dioxide
Silicon Dioxide (SiO₂) exhibits very low bioavailability—often less than 20%. Its poor solubility and limited absorption present challenges for achieving meaningful clinical outcomes.
Orthosilicic Acid
Orthosilicic acid (OSA) is a bioavailable, soluble form of silicium found naturally in the body. However, OSA typically begins to polymerize and lose bioavailability above a pH of 3.5. This instability results in poor absorption.
THE SOLUTION IS MESOPOROSIL®
Mesoporosil® represents a breakthrough in silicium delivery, offering superior stability, solubility, and bioavailability compared to conventional forms like orthosilicic acid, silicon dioxide and traditional plant-based sources.
Thanks to its advanced mesoporous structure, Mesoporosil® optimizes silicium exposure and enables a controlled release, dramatically increasing the likelihood of uptake and assimilation. It maintains its solubility across the full intestinal pH range (6.0 to 7.5), ensuring consistent bioavailability without the need for liquid formulations. This makes it a more convenient and reliable option for inclusion in tablets, capsules, and powders.
In a comparative dissolution test, Mesoporosil® demonstrated superior solubility compared to other silicium sources. This translates to greater absorption in the intestines, more formulation flexibility, and a consistent and predictable performance across product types.
THE MESOPOROSIL® DIFFERENCE
For formulators seeking a next-generation silicium solution, Mesoporosil® delivers clear advantages: unmatched bioavailability, pH-stable solubility, and broad application potential. It’s not just a new source of silicium—it’s a new standard.
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Bloosil® is a certified organic, vegan, plant-based silicium from Maypro. Bloosil® delivers the same clinically supported benefits as Mesoporosil®—but from a bamboo-derived source. This highly soluble bamboo silica extract supports collagen formation and strengthens hair by enhancing the keratin structure within hair strands. In a human clinical study, Bloosil® was shown to promote youthful-looking hair with improved shine, silkiness, reduced hair loss, and stronger roots.
