Few nutritional segments are developing at greater speed, or with greater zeal, than women’s health. Growing at a CAGR of 8.5%, the global women’s health supplement market is projected to surpass $75 billion by 2030 (Source: Grand View Research). The surge in growth can be partially credited to a cultural shift driven by women for women. In the natural health space, we see it manifesting as women prioritizing not only a healthy appearance but also a healthy experience at every life stage. From mitigating menopause-driven muscle and bone loss to perimenopausal weight gain, loss of libido, and sleep disruption to supporting a range of pre-menstrual and menstruation symptoms, women want real solutions that help to maintain or restore quality of life.
If you are developing products for women’s health and wellbeing, please reach out if we can provide you with clinical research, documentation, and samples on any of these ingredients.
Venetron®: PMS Relief and Menstrual Support
Venetron® is a patented, clinically studied botanical extract of Apocynum venetum standardized to 2% hyperoside and 2% isoquercetin—key flavonoids that are foundational to its benefits. Also available in a water-soluble form (Venetron®-W), this ingredient can support the emotional and physical challenges women face throughout the month.
Research shows that just 50 mg of Venetron® per day can help reduce perceived stress and anxiety, improve sleep quality, and promote a more balanced mood. Its multi-pathway mechanism includes:
- Stimulating natural melatonin production
- Supporting healthy serotonin levels
- Lowering the stress marker chromogranin A
- Activating GABA receptors
A recent clinical trial demonstrated Venetron®’s ability to ease PMS-related mood swings, concentration, and behavioral changes—helping women feel calmer, sleep better, and maintain well-being before the menstrual cycle.
During menstruation, ingestion of Venetron® improved pain, poor concentration, and self control with fewer complaints on symptoms associated with menstruation.
Applications
- PMS Comfort
- Menstrual Comfort
- Stress and Mood Support
- Sleep Support
Download the Venetron® Product Brief
AKK PROBIO™: Gut Microbiome Innovation for Metabolic Health
Perimenopause and menopause are linked to fat gain and insulin resistance, caused in part by estrogen fluctuations that alter metabolism and body composition. Positioning your formulations for both stages means focusing on metabolic resilience, not quick fixes.
AKK PROBIO™, winner of the 2025 Ingredient Idol for Weight Management, is a proprietary strain of Akkermansia muciniphila that was selected after years of research and the evaluation of over 200 Akkermansia strains. AKK PROBIO™ supports a healthy gut barrier, contributes to the production of short chain fatty acids (SCFAs) that promote energy, and facilitates metabolic balance by aiding insulin sensitivity and GLP-1 production.
AKK PROBIO™ is designed to support gut barrier integrity by promoting mucin turnover within the intestinal mucus layer—an essential interface between the microbiome and the gut lining. This targeted activity helps shape a more favorable microbial environment by increasing beneficial bacteria and reducing less desirable species.
Akkermansia muciniphila, a foundational next-generation probiotic, further supports intestinal health through the production of key short-chain fatty acids (SCFAs), including acetate and propionate, which serve as important energy sources for intestinal cells.
Collectively, these microbiome-driven effects help support a resilient and balanced gut ecosystem through three primary mechanisms:
- Promotion of mucin turnover to support a healthy gut barrier
- Generation of SCFA's to help fuel intestinal cells
- Modulation of metabolic and hormomnal signaling, including support for GLP-1, leptin and GIP peptide activity.
Available in both the live and inactive forms, AKK PROBIO™ enhances Akkermansia abundance and delivers clinically validated benefits across diverse applications.
Download the product brief to learn more.
AKK PROBIO™: Requesting Specifications
Clonapure®: Creatine Complex for Strength, Energy, and Cognitive Health
Women naturally produce less creatine than men, and these levels decline further with age and hormonal changes, particularly during perimenopause through post-menopause. Aging also introduces sarcopenia—the gradual loss of muscle mass and strength. This makes supplementation more impactful for women than men because the relative improvement is higher compared to men.
Studies show that creatine combined with resistance training helps older women maintain lean muscle mass and strength, improving mobility and reducing fall risk. It also helps strengthen bones as women age.
Additionally, creatine is recognized for its ability to boost brain energy to support memory, focus and mental sharpness. The decline in which can signal the onset of perimenopause and menopause for women.
Clonapure® is an advanced creatine complex comprised of creatine monohydrate, phosphocreatine, and phosphate that offers quicker absorption and enhanced ATP regeneration.
Applications
- Women's Health
- Active Nutrition
- Healthy Aging
Interested in learning more about this exciting new form of creatine supported by published human clinical research? Download the Product Brief or contact us directly to request specifications and research.
Read the Clonapure® Product Brief
Mesoporosil®: Advanced Silicon for Bone Support
Mesoporosil® is a mesoporous silica-based ingredient designed to enhance collagen synthesis and bone mineralization. Mesoporosil® supports bone health by promoting the natural remodeling process essential for strong, functional bones. Bone is a dynamic tissue constantly undergoing renewal through the coordinated actions of osteoclasts (which break down old bone) and osteoblasts (which build new bone). Bioavailable silicon, such as that provided by Mesoporosil®, has been shown to stimulate the proliferation and differentiation of osteoblasts, enhance type I collagen synthesis, and assist in the cross-linking of collagen and glycosaminoglycans (GAG), all of which contribute to a stronger, more resilient bone and joint matrix.
Human trials show improved bone density and reduced fracture risk when combined with vitamin K2 and vitamin D3 supplementation.
Applications
- Bone and joint support
- Healthy hair, skin and nails
Thanks to its advanced mesoporous structure and solubility, Mesoporosil® optimizes silicon exposure and enables a controlled release, dramatically increasing the likelihood of uptake and assimilation. It maintains its solubility across the full intestinal pH range (6.0 to 7.5), ensuring consistent bioavailability without the need for liquid formulations. This makes it a more convenient and reliable option for inclusion in tablets, capsules, and powders.
Maypro’s clinically proven nutraceuticals, access to high-quality functional ingredients, reliable sourcing, and safety and quality documentation can provide you with the consistency and trust you need. Let’s work together to help shape the future of women’s natural health.
UPCOMING EVENTS
Natural Products EXPO WEST
March 4-6, 2026
Anaheim Convention Center, CA
Booth #4481
Nutri Ingredients Summit
March 31-1 April, 2026
São Paulo Expo, Brazil
Booth #1-80
